Stereochemistry of lignans in Phaleria macrocarpa (Scheff.) Boerl.

نویسندگان

  • Ahmad Saufi
  • Cosima B I von Heimendahl
  • A Wilhelm Alfermann
  • Elisabeth Fuss
چکیده

Phaleria macrocarpa (Scheff.) Boerl., a member of the Thymelaeaceae, is traditionally used in Indonesia as medicinal plant against cancer. In this context, we isolated the lignans pinoresinol, lariciresinol and matairesinol from different parts of this plant. The enantiomeric composition of these lignans was determined by chiral column analysis. Pinoresinol and lariciresinol were mixtures of both enantiomers with (79 +/- 4)% and (55 +/- 6)% enantiomeric excess for the (-)-enantiomers, respectively, whereas matairesinol was found as pure (+)-enantiomer.

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عنوان ژورنال:
  • Zeitschrift fur Naturforschung. C, Journal of biosciences

دوره 63 1-2  شماره 

صفحات  -

تاریخ انتشار 2008